Dom speaks:
Just because it's late and I'm feeling silly, I'll drop you a hint. Think of it as me being Reinhart and the person offscreen as Annerose. Let's see who gets THAT reference... ;p

M3G4133T = Megaleet
Ed-chan no Ribbon is a pun on the anime series Hime-chan no Ribbon. In the third panel, Ed is chanting the spell that Hime-chan uses to undo her disguise magic, while the show's opening theme song plays down in the corner.
The shouts of "Noooooooooo!" in the fourth panel are reminiscent of Pedro from Excel Saga.